Crataegus tanacetifolia leaf extract prevents L-NAME-induced hypertension in rats: A morphological study

Koçyıldız Z. Ç., Birman H., Olgaç V., Akgun-Dar K., Melikoğlu G., Meriçli A. H.

PHYTOTHERAPY RESEARCH, vol.20, no.1, pp.66-70, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1002/ptr.1808
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.66-70
  • Keywords: Crataegus, cardiovascular, L-NAME, arterial blood pressure, lipid levels, arterial wall, OXIDE SYNTHASE INHIBITOR, FLAVONOID QUERCETIN, BLOOD-PRESSURE, RENAL-FUNCTION, CHOLESTEROL, RABBITS, DRUGS
  • Istanbul University Affiliated: Yes


Crataegus (hawthorn) has long been used as a folk medicine all around the world. Most of the studies with Crataegus species focus on effects on heart failure and cardiovascular disease. The pharmacological effects of Crataegus have been attributed mainly to the content of flavonoids, procyanidin, aromatic acid and cardiotonic amines.