Is stereotactic body radiotherapy a treatment option for pelvic recurrences?


Dagoglu N., Karaman S., Senyurek S., Okutan M., Kemikler G., Kaytan Saglam E., ...More

TURK ONKOLOGI DERGISI-TURKISH JOURNAL OF ONCOLOGY, no.2, pp.45-50, 2015 (ESCI) identifier identifier

Abstract

OBJECTIVES When surgery is not adequate, stereotactic body radiotherapy (SBRT) has been used for recurrent cancers. We report the outcomes of case series with pelvic recurrences from colorectal cancer irradiated with SBRT. METHODS Robotic Stereotactic Radiotherapy system was used. The dose fractionation scheme was individualized based on tumor volume and location and prior radiation dose. RESULTS Between February 2010 and December 2014, four patients were treated. Treatment regions were pelvic side wall for two patients and presacral for two patients. SBRT doses were 24 Gy in 3 fractions for three patients and 36.25 Gy in 5 fractions for one patient. One patient treated for pelvic side wall recurrence developed symptomatic noropathy at fist year. CONCLUSION Local recurrence in pelvis after modern combined modality treatment for colorectal cancer is rare. However it presents a therapeutic dilemma when it occurs; often symptomatic and eventually life threatening. SBRT can be a useful modality in this setting.