Hemodiafiltration Is Associated With Reduced Inflammation and Increased Bone Formation Compared With Conventional Hemodialysis in Children: The HDF, Hearts and Heights (3H) Study

Fischer, Dagmar-Christiane; Smith, Colette; De Zan, Francesca; Bacchetta, Justine; BAKKALOĞLU EZGÜ, SEVCAN; AĞBAŞ, Ayşe; Anarat, Ali; Aoun, Bilal; Askiti, Varvara; Azukaitis, Karolis; KARABAY BAYAZIT, AYSUN; KAPLAN BULUT, İPEK; CANPOLAT, Nur; Borzych-Duzalka, Dagmara; Duzova, Ali; Habbig, Sandra; Krid, Saoussen; Licht, Christoph; Litwin, Mieczyslaw; Obrycki, Lukasz; Paglialonga, Fabio; Rahn, Anja; Ranchin, Bruno; Samaille, Charlotte; Shenoy, Mohan; Sinha, Manish; Spasojevic, Brankica; Stefanidis, Constantinos; Vidal, Enrico; Yilmaz, Alev; Fischbach, Michel; Schaefer, Franz; Schmitt, Claus; Shroff, Rukshana

doi:10.1016/j.ekir.2021.06.025

Hemodiafiltration Is Associated With Reduced Inflammation and Increased Bone Formation Compared With Conventional Hemodialysis in Children: The HDF, Hearts and Heights (3H) Study

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Fischer D., Smith C., De Zan F., Bacchetta J., BAKKALOĞLU EZGÜ S. A., AĞBAŞ A., ...More

KIDNEY INTERNATIONAL REPORTS, vol.6, no.9, pp.2358-2370, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 6 Issue: 9
Publication Date: 2021
Doi Number: 10.1016/j.ekir.2021.06.025
Journal Name: KIDNEY INTERNATIONAL REPORTS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
Page Numbers: pp.2358-2370
Keywords: hemodiafiltration, hemodialysis, inflammation, mineral bone disease, pediatric nephrology, CHRONIC KIDNEY-DISEASE, GROWTH-FACTOR 23, LEFT-VENTRICULAR HYPERTROPHY, TNF-ALPHA, ONLINE HEMODIAFILTRATION, CLINICAL-PRACTICE, VASCULAR CALCIFICATION, SYSTEMIC INFLAMMATION, ALKALINE-PHOSPHATASE, BIOCHEMICAL MARKERS
Istanbul University Affiliated: Yes

Abstract

Background: Patients on dialysis have a high burden of bone-related comorbidities, including fractures. We report a post hoc analysis of the prospective cohort study HDF, Hearts and Heights (3H) to determine the prevalence and risk factors for chronic kidney disease-related bone disease in children on hemodiafiltration (HDF) and conventional hemodialysis (HD).