Examination of the expression levels of MACC1, Filamin A and FBXW7 genes in colorectal cancer patients
NORTHERN CLINICS OF ISTANBUL, cilt.7, sa.1, ss.1-5, 2020 (ESCI, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 7 Sayı: 1
- Basım Tarihi: 2020
- Doi Numarası: 10.14744/nci.2019.26780
- Dergi Adı: NORTHERN CLINICS OF ISTANBUL
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.1-5
- İstanbul Üniversitesi Adresli: Evet
Özet
OBJECTIVE: Colorectal cancer (CRC) is the third most common type of cancer observed in cancer-related mortality because it has a high metastasis ratio. This study aims to investigate the expression levels of several genes, including metastasis-related colon cancer 1 (MACC1), Filamin A (FLNA), F-box/WD repeat-containing protein 7 (FBXW7), which has an important role in cell signaling, migration and adhesion through the remodeling of the cell skeleton.