Examination of the expression levels of MACC1, Filamin A and FBXW7 genes in colorectal cancer patients

Yesilkaya F., Tastekin D., Al Saadoni H., Ergen A., Pence S.

NORTHERN CLINICS OF ISTANBUL, vol.7, no.1, pp.1-5, 2020 (ESCI, TRDizin) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.14744/nci.2019.26780
  • Journal Name: NORTHERN CLINICS OF ISTANBUL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1-5
  • Istanbul University Affiliated: Yes

Abstract

OBJECTIVE: Colorectal cancer (CRC) is the third most common type of cancer observed in cancer-related mortality because it has a high metastasis ratio. This study aims to investigate the expression levels of several genes, including metastasis-related colon cancer 1 (MACC1), Filamin A (FLNA), F-box/WD repeat-containing protein 7 (FBXW7), which has an important role in cell signaling, migration and adhesion through the remodeling of the cell skeleton.