Examination of the expression levels of MACC1, Filamin A and FBXW7 genes in colorectal cancer patients

Yesilkaya F., Tastekin D., Al Saadoni H., Ergen A., Pence S.

NORTHERN CLINICS OF ISTANBUL, cilt.7, sa.1, ss.1-5, 2020 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.14744/nci.2019.26780
  • Dergi Adı: NORTHERN CLINICS OF ISTANBUL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1-5
  • İstanbul Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Colorectal cancer (CRC) is the third most common type of cancer observed in cancer-related mortality because it has a high metastasis ratio. This study aims to investigate the expression levels of several genes, including metastasis-related colon cancer 1 (MACC1), Filamin A (FLNA), F-box/WD repeat-containing protein 7 (FBXW7), which has an important role in cell signaling, migration and adhesion through the remodeling of the cell skeleton.