Effects of local anesthetics on wound healing

Kesici S., Kesici U., ULUSOY H., Erturkuner P., Turkmen A., Arda O.

REVISTA BRASILEIRA DE ANESTESIOLOGIA, vol.68, no.4, pp.375-382, 2018 (SCI-Expanded) identifier identifier


Introduction: Local anesthetic infiltration is used widely for post-operative analgesia in many situations. However the effects of local anesthetics on wound healing are not demonstrated clearly. This study planned to evaluate the effects of lidocaine, prilocaine, bupivacaine and levobupivacaine on wound healing, primarily on wound tensile strength and on collagen ultrastructure.