Betaine treatment decreased serum glucose and lipid levels, hepatic and renal oxidative stress in streptozotocin-induced diabetic rats
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.43, no.4, pp.343-351, 2018 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 43 Issue: 4
- Publication Date: 2018
- Doi Number: 10.1515/tjb-2016-0183
- Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.343-351
- Keywords: Diabetes mellitus, Betaine, Oxidative stress, Liver, Kidney, Rat, INDUCED NEPHROTOXICITY, LIVER, METFORMIN, SUPPLEMENTATION, HOMOCYSTEINE, NEPHROPATHY, METABOLISM, INJURY, ASSAY, ACID
- Istanbul University Affiliated: Yes
Abstract
Objective: The present study was aimed to investigate the effects of betaine (BET) on streptozotocin (STZ)-induced diabetes mellitus (DM) in rats. Additionally, the efficiency of BET was compared with metformin (MET), a standard oral antidiabetic drug.