Betaine treatment decreased serum glucose and lipid levels, hepatic and renal oxidative stress in streptozotocin-induced diabetic rats


Evran B., Aydin A. F. , Uguralp B., Sar M., Dogru-Abbasoglu S. , Uysal M.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.43, no.4, pp.343-351, 2018 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1515/tjb-2016-0183
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.343-351
  • Keywords: Diabetes mellitus, Betaine, Oxidative stress, Liver, Kidney, Rat, INDUCED NEPHROTOXICITY, LIVER, METFORMIN, SUPPLEMENTATION, HOMOCYSTEINE, NEPHROPATHY, METABOLISM, INJURY, ASSAY, ACID

Abstract

Objective: The present study was aimed to investigate the effects of betaine (BET) on streptozotocin (STZ)-induced diabetes mellitus (DM) in rats. Additionally, the efficiency of BET was compared with metformin (MET), a standard oral antidiabetic drug.