Betaine treatment decreased serum glucose and lipid levels, hepatic and renal oxidative stress in streptozotocin-induced diabetic rats

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Evran B., Aydin A. F., Uguralp B., Sar M., Dogru-Abbasoglu S., Uysal M.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.43, sa.4, ss.343-351, 2018 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 43 Sayı: 4
• Basım Tarihi: 2018
• Doi Numarası: 10.1515/tjb-2016-0183
• Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.343-351
• Anahtar Kelimeler: Diabetes mellitus, Betaine, Oxidative stress, Liver, Kidney, Rat, INDUCED NEPHROTOXICITY, LIVER, METFORMIN, SUPPLEMENTATION, HOMOCYSTEINE, NEPHROPATHY, METABOLISM, INJURY, ASSAY, ACID
• İstanbul Üniversitesi Adresli: Evet

Özet

Objective: The present study was aimed to investigate the effects of betaine (BET) on streptozotocin (STZ)-induced diabetes mellitus (DM) in rats. Additionally, the efficiency of BET was compared with metformin (MET), a standard oral antidiabetic drug.