Comparison of epidural analgesia combined with general anesthesia and general anesthesia for postoperative cognitive dysfunction in elderly patients.

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Orhun G., Sungur Z., Koltka K., Karadeniz M., Yavru H. A., Gurvit H., ...Daha Fazla

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, cilt.26, sa.1, ss.30-36, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.14744/tjtes.2019.04135
  • Dergi Adı: Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.30-36
  • Anahtar Kelimeler: Cognitive dysfunction, elderly, epidural analgesia, general anesthesia, postoperative pain, REGIONAL ANESTHESIA, NONCARDIAC SURGERY, NEUROINFLAMMATION, DELIRIUM, IMPAIRMENT, PROPOFOL, SCREEN
  • İstanbul Üniversitesi Adresli: Evet

Özet

BACKGROUND: Cognitive dysfunction in the early postoperative course is common for the elderly population. Anesthetic management may affect postoperative cognitive decline. Effective analgesia, early recovery and modulation of the stress response are advantages of neuraxial blocks. This study aims to compare the effects of general anesthesia and the combination of general anesthesia with epidural analgesia for postoperative cognitive dysfunction (POCD). We hypothesized that neuraxial block combined with general anesthesia (GA) would have a favorable influence on POCD prevention.