rac-2-hydroxy-2,8-dimethyl-4-morpholinoethyl-1-thia-4-azaspiro[4.5]decan-3-one
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, cilt.64, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 64
- Basım Tarihi: 2008
- Doi Numarası: 10.1107/s1600536808022447
- Dergi Adı: ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- İstanbul Üniversitesi Adresli: Evet
Özet
The title compound, C(16)H(28)N(2)O(3)S, is dimerized by inversion symmetry-related intermolecular O-H center dot center dot center dot N hydrogen bonding, forming an R(2)(2)(16) motif. The dimers are also linked through intermolecular C-H center dot center dot center dot O hydrogen bonding. The compound is chiral with a stereogenic centre located in the thiazole ring, but in the crystal structure it forms a racemate. The thiazole ring has an envelope conformation, while the cyclohexane and morpholine rings adopt chair conformations.