rac-2-hydroxy-2,8-dimethyl-4-morpholinoethyl-1-thia-4-azaspiro[4.5]decan-3-one


AKKURT M., Yalcin S. P., Klip N. T., BÜYÜKGÜNGÖR O.

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, vol.64, 2008 (SCI-Expanded) identifier identifier identifier

Abstract

The title compound, C(16)H(28)N(2)O(3)S, is dimerized by inversion symmetry-related intermolecular O-H center dot center dot center dot N hydrogen bonding, forming an R(2)(2)(16) motif. The dimers are also linked through intermolecular C-H center dot center dot center dot O hydrogen bonding. The compound is chiral with a stereogenic centre located in the thiazole ring, but in the crystal structure it forms a racemate. The thiazole ring has an envelope conformation, while the cyclohexane and morpholine rings adopt chair conformations.