MAGEB2 is Activated by Promoter Demethylation in Head and Neck Squamous Cell Carcinoma

Pattani, Kavita; Soudry, Ethan; Glazer, Chad; Ochs, Michael; Wang, Hao; Schussel, Juliana; Sun, Wenyue; Hennessey, Patrick; Mydlarz, Wojciech; Loyo, Myriam; Demokan, SEMRA; Smith, Ian; Califano, Joseph

doi:10.1371/journal.pone.0045534

MAGEB2 is Activated by Promoter Demethylation in Head and Neck Squamous Cell Carcinoma

Pattani K. M., Soudry E., Glazer C. A., Ochs M. F., Wang H., Schussel J., ...Daha Fazla

PLOS ONE, cilt.7, sa.9, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 7 Sayı: 9
Basım Tarihi: 2012
Doi Numarası: 10.1371/journal.pone.0045534
Dergi Adı: PLOS ONE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
İstanbul Üniversitesi Adresli: Evet

Özet

Purpose: Although promoter hypermethylation has been an accepted means of tumor suppressor gene inactivation, activation of otherwise normally repressed proto-oncogenes by promoter demethylation has been infrequently documented.