Quetiapine Fumarate Extended-release Tablet Formulation Design Using Artificial Neural Networks


Ozcelik E., Mesut B. , Aksu B., Ozsoy Y.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, ss.213-221, 2017 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 14 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tjps.97720
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Sayfa Sayısı: ss.213-221

Özet

Objectives: This design study was implemented within the scope of the quality by design approach, which included the "International Conference on Harmonization" guidelines. We evaluated the quality of a modified-release tablet formulation of quetiapine fumarate, which was designed using artificial neural networks (ANN), and determined a new formulation that was similar to the reference product.