Quetiapine Fumarate Extended-release Tablet Formulation Design Using Artificial Neural Networks
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, sa.3, ss.213-221, 2017 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 3
- Basım Tarihi: 2017
- Doi Numarası: 10.4274/tjps.97720
- Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.213-221
- İstanbul Üniversitesi Adresli: Evet
Özet
Objectives: This design study was implemented within the scope of the quality by design approach, which included the "International Conference on Harmonization" guidelines. We evaluated the quality of a modified-release tablet formulation of quetiapine fumarate, which was designed using artificial neural networks (ANN), and determined a new formulation that was similar to the reference product.