Prothrombotic gene mutations and Crohn's disease; is there any association?


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OVER-HAMZAOGLU H., Abaci N. , TURE F., ALKIM C., TEZEL A., AVSAR E. , ...More

HEPATO-GASTROENTEROLOGY, vol.52, no.65, pp.1467-1469, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 65
  • Publication Date: 2005
  • Title of Journal : HEPATO-GASTROENTEROLOGY
  • Page Numbers: pp.1467-1469
  • Keywords: inflammatory bowel disease, thromboembolism, FV gene and prothrombin, G20210A gene mutations, Crohn's disease, INFLAMMATORY-BOWEL-DISEASE, ACTIVATED PROTEIN-C, V-LEIDEN MUTATION, VENOUS THROMBOSIS, COAGULATION, RESISTANCE, THROMBOPHILIA, G20210A, REGION, RISK

Abstract

Background/Aims: Patients with inflammatory bowel disease have an increased tendency for thromboembolism. In this study we aimed to determine the frequency of FV gene and Prothrombin G20210A gene mutations in a group of patients with Crohn's Disease (CD) and estimate its correlation with disease activity and clinical subtype.