Histopathological evidence for an association of inflammation with ductal pin-like lesions but not with ductal adenocarcinoma in the prostate of the noble rat


Bernoulli J., Yatkin E., Laakso A., Anttinen M., Bosland M., Vega K., ...More

PROSTATE, vol.68, no.7, pp.728-739, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 7
  • Publication Date: 2008
  • Doi Number: 10.1002/pros.20719
  • Journal Name: PROSTATE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.728-739
  • Istanbul University Affiliated: No

Abstract

BACKGROUND. Chronic inflammation may contribute to the development of prostate cancer. The goal of this study was to determine the possible association of prostatic inflammation, prostatic intraepithelial neoplasia (PIN)-like lesion, and prostate cancer, and to assess the androgen and estrogen dependency of the early steps of carcinogenesis.