Plasma Lp(a) and t-PA-PAI-1 complex levels in coronary heart disease

Suer S., Ulutin T., Sonmez H. A., Kokoglu E. H., Ucisik N., Bayram C., ...Daha Fazla

THROMBOSIS RESEARCH, cilt.83, sa.1, ss.77-85, 1996 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 83 Sayı: 1
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1016/0049-3848(96)00105-3
  • Dergi Adı: THROMBOSIS RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.77-85
  • İstanbul Üniversitesi Adresli: Evet

Özet

In this study we investigated serum Lp(a) and plasma t-PA-PAI-1 complex levels in patients with coronary heart disease (CHD). Serum to,tal cholesterol, triglyceride, LDL and VDL cholesterol levels (p<0.001) and HDL cholesterol levels (p<0.01) in patients group were found to be significantly different from those in control group. The mean Lp(a) and t-PA-PAI-1 complex levels in patients with coronary heart disease were significantly higher as compared to control group (p<0.001). This data indicate that the elevated levels of serum Lp(a) and plasma t-PA-PAI-1 complex may play an important role in the pathogenesis of coronary atherosclerosis.