Melatonin ameliorates oxidative damage in hyperglycemia-induced liver injury


Korkmaz G. G. , Uzun H. , Cakatay U. , Aydin S.

CLINICAL AND INVESTIGATIVE MEDICINE, vol.35, no.6, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 6
  • Publication Date: 2012
  • Title of Journal : CLINICAL AND INVESTIGATIVE MEDICINE

Abstract

Purpose: Melatonin (N-acetyl-5-methoxy-tryptamine) is synthesized mainly by the pineal gland and its antioxidant properties have been demonstrated both in short and long term studies. Our aim was to clarify the effects of hyperglycemia and to administer melatonin on lipid peroxidation, protein oxidation and oxidative DNA damage in rat.