Association between non-coding polymorphisms of HOPX gene and syncope in hypertrophic cardiomyopathy.


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Gulec C. , Abaci N. , Bayrak F., BAYRAK E. K. , KAHVECI G., Guven C., ...Daha Fazla

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, cilt.14, ss.617-24, 2014 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 14 Konu: 7
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5152/akd.2014.4972
  • Dergi Adı: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • Sayfa Sayıları: ss.617-24

Özet

Objective: Homeodomain Only Protein X (HOPX) is an unusual homeodomain protein which regulates Serum Response Factor (SRF) dependent gene expression. Due to the regulatory role of HOPX on SRF activity and the regulatory role of SRF on cardiac hypertrophy, we aimed to investigate the relationship between HOPX gene variations and hypertrophic cardiomyopathy (HCM).