NUCLEOLAR ORGANIZER REGIONS IN PITUITARY-GLAND ADENOMAS


BAYINDIR C., DOGAN O., UNAL F., DERVISOGLU S.

CYTOPATHOLOGY, vol.3, no.4, pp.223-229, 1992 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 3 Issue: 4
  • Publication Date: 1992
  • Doi Number: 10.1111/j.1365-2303.1992.tb00512.x
  • Title of Journal : CYTOPATHOLOGY
  • Page Numbers: pp.223-229

Abstract

Nucleolar organizer regions are DNA segments concerned with the synthesis of ribosomal RNA (rRNA). Some specific proteins related to NORs can be demonstrated by a silver technique and are then referred to as Ag-NORs. The mean number of Ag-NORs per cell has been used as a marker of cell proliferation in recent years and there is some evidence to suggest that Ag-NOR counts can be used to differentiate between normal and neoplastic cells.