Successful Management of Chronic Refractory Immune Thrombocytopenia with Laparoscopic Splenectomy in a Patient with Acute Promyelocytic Leukemia

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Atıf İçin Kopyala

Eskazan A. E., Salihoglu A., Gulturk E., Aydin S. O., Tuzuner N., Aydin Y.

INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION, cilt.29, sa.3, ss.173-177, 2013 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 29 Sayı: 3
• Basım Tarihi: 2013
• Doi Numarası: 10.1007/s12288-012-0173-8
• Dergi Adı: INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.173-177
• İstanbul Üniversitesi Adresli: Evet

Özet

Acute promyelocytic leukemia (APL) is a particular type of acute myeloid leukemia with characteristic biological and clinical features, the frequent association at diagnosis of a severe hemorrhagic diathesis. Immune thrombocytopenia (ITP) is a common autoimmune disease characterized by low platelet counts and an increased risk of bleeding. Here we present a patient with the diagnosis of APL who achieved and maintained a remission with an induction consisting of idarubicin and ATRA, and then developed corticosteroid refractory ITP which is successfully treated with laparoscopic splenectomy.