Evidence for potential involvement of pro-inflammatory adipokines in the pathogenesis of idiopathic intracranial hypertension

Samanci B., Samancı Y., Tuzun E., Altiokka-Uzun G., Ekizoglu E., Icoz S., ...Daha Fazla

CEPHALALGIA, cilt.37, sa.6, ss.525-531, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1177/0333102416650705
  • Dergi Adı: CEPHALALGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.525-531
  • Anahtar Kelimeler: Adipokines, cytokines, idiopathic intracranial hypertension, nesfatin, obesity, TNF-ALPHA, CEREBROSPINAL-FLUID, INSULIN-RESISTANCE, SERUM LEPTIN, NESFATIN-1, EXPRESSION, IL-1-BETA, INDUCTION, BRAIN, IL-6
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Although specific role players are currently unknown, contribution of inflammatory mediators has been suggested in the pathophysiology of idiopathic intracranial hypertension (IIH), which is a disease more prevalent in obese female individuals of childbearing age. We aimed to investigate the levels of adipokines and cytokines to demonstrate possible markers for inflammation that participate in IIH pathophysiology and their association with clinical features of IIH.