A review on the dosimetrical and radiobiological prediction of radiation-induced hypothyroidism in radiation therapy of head-and-neck cancer, breast cancer, and Hodgkin's lymphoma survivors


Mohammad Namdar A., Mohammadzadeh M., Okutan M. , Mesbahi A.

POLISH JOURNAL OF MEDICAL PHYSICS AND ENGINEERING, cilt.24, ss.137-148, 2018 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 24 Konu: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2478/pjmpe-2018-0020
  • Dergi Adı: POLISH JOURNAL OF MEDICAL PHYSICS AND ENGINEERING
  • Sayfa Sayıları: ss.137-148

Özet

A review on the radiobiological modeling of radiation-induced hypothyroidism after radiation therapy of head-and-neck cancers, breast cancer, and Hodgkin's lymphoma is presented. The current review is based on data relating to dose-volume constrains and normal tissue complication probability (NTCP) as a function of either radiobiological or (pre)treatment-clinical parameters. Also, these data were explored in order to provide more helpful criteria for radiobiological optimization of treatment plans involving thyroid gland as a critical normal organ.