The effect of transforming growth factor beta 1 (TGF-beta 1) on the regenerate bone in distraction osteogenesis - A biomechanical, histologic and immunohistochemical study on rabbits


OZKAN K., ERALP L., KOCAOGLU M., Ahishali B., BILGIC B., Mutlu Z., ...Daha Fazla

GROWTH FACTORS, cilt.25, sa.2, ss.101-107, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1080/08977190701352594
  • Dergi Adı: GROWTH FACTORS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.101-107
  • İstanbul Üniversitesi Adresli: Evet

Özet

Distraction osteogenesis is a well established clinical treatment for limb length dicrepancy and skeletal deformities. Transforming growth factor beta 1 (TGF-beta 1) is a multifunctional peptide which controls proliferation and expression of cells specific to bone like chondrocytes, osteoblasts, osteoclasts including mesenchymal precursor cells.