The effect of transforming growth factor beta 1 (TGF-beta 1) on the regenerate bone in distraction osteogenesis - A biomechanical, histologic and immunohistochemical study on rabbits


OZKAN K., ERALP L., KOCAOGLU M. , Ahishali B. , BILGIC B., Mutlu Z. , ...More

GROWTH FACTORS, vol.25, no.2, pp.101-107, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1080/08977190701352594
  • Title of Journal : GROWTH FACTORS
  • Page Numbers: pp.101-107

Abstract

Distraction osteogenesis is a well established clinical treatment for limb length dicrepancy and skeletal deformities. Transforming growth factor beta 1 (TGF-beta 1) is a multifunctional peptide which controls proliferation and expression of cells specific to bone like chondrocytes, osteoblasts, osteoclasts including mesenchymal precursor cells.