Impact of Nonosseous Findings on F-18-NaF PET/CT in a Patient with Ductal Breast Carcinoma

Kuyumcu S., Adalet I., Isik E. G., Unal S.

NUCLEAR MEDICINE AND MOLECULAR IMAGING, cilt.48, sa.1, ss.72-74, 2014 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s13139-013-0235-3
  • Dergi Adı: NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.72-74
  • Anahtar Kelimeler: F-18-NaF PET/CT, F-18-FDG PET/CT, Bone metastasis, Breast carcinoma, F-18-FLUORIDE, METASTASES
  • İstanbul Üniversitesi Adresli: Evet

Özet

F-18-NaF was used as a bone-seeking PET tracer for skeletal imaging until the introduction of the widely available Tc-99m-labeled bone agents. However, there is renewed clinical interest in F-18-NaF since prior technical and logistic limitations to its routine use are no longer present, and, as a consequence, it is likely that uptake unrelated to bone and non-osseous findings will be encountered more frequently. As a result of tumoral necrosis, soft tissue metastases may demonstrate F-18-NaF avidity due to dystrophic calcification. On the other hand, all non-osseous findings, whether F-18-NaF avid or not, may provide important diagnostic information that may alter the course of the disease, including treatment options. Herein we present a patient with ductal carcinoma of the breast in whom findings unrelated to the skeletal system in F-18-NaF PET/CT altered the treatment strategy.