SARC-F Questionnaire Detects Frailty in Older Adults.
The journal of nutrition, health & aging, cilt.25, sa.4, ss.448-453, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 25 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.1007/s12603-020-1543-9
- Dergi Adı: The journal of nutrition, health & aging
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Abstracts in Social Gerontology, AgeLine, CAB Abstracts, CINAHL, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.448-453
- Anahtar Kelimeler: Sarcopenia, frailty, screening, diagnosis, geriatric practice
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- İstanbul Üniversitesi Adresli: Evet
Özet
Background/objectives: The physical phenotype of frailty, described by Fried et al., shows significant overlap with sarcopenia. EWGSOP2 recommends the SARC-F questionnaire to screen for sarcopenia. Considering common features between both conditions, we aimed to investigate whether the SARC-F questionnaire could also be a valid and reliable tool to screen or evaluate frailty.
Design: Retrospective, cross-sectional.
Setting: Istanbul University Istanbul Faculty of Medicine.
Participants: A total of 447 older adults (70.7% female, mean age: 74.5±6.6 years).
Measurements: Frailty was assessed by the modified Fried scale. SARC-F questionnaire was performed by all participants. We used a receiver operating characteristics curve to obtain SARC-F cut-off values to detect frailty, and calculated the area under the curve and 95% confidence interval.
Results: There were 93 (20.8%) older adults with frailty according to the modified Fried scale. SARC-F cut-off ≥1 had 91.4% sensitivity and 44.9% specificity. SARC-F cut-off ≥2 presented the best balance between sensitivity and specificity (sensitivity: 74.1% vs. specificity: 73.7%) to identify frailty (area under curve: 0.807; 95% confidence interval: 0.76-0.84, p<0.001). SARC-F ≥4 had high specificity of 92.6% with a sensitivity of 46.2%.
Conclusion: We suggest that SARC-F ≥1 point can be used to screen for frailty with high sensitivity, and SARC-F ≥4 can be used to diagnose frailty with high specificity. SARC-F may be used to evaluate frailty in usual geriatric practice.