Coexistence of regression and tumor infiltrating lymphocytes is associated with more favorable survival in melanoma.

Tas F., Erturk K.

Journal of cancer research and clinical oncology, vol.147, pp.2721-2729, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 147
  • Publication Date: 2021
  • Doi Number: 10.1007/s00432-021-03565-y
  • Journal Name: Journal of cancer research and clinical oncology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.2721-2729
  • Keywords: Melanoma, Regression, Tumor infiltrating lymphocytes, Survival
  • Istanbul University Affiliated: Yes

Abstract

Purpose Melanoma is one of the highly immunogenic malignancies, and histological regression (HR) and tumor infiltrating lymphocytes (TILs) represent early signs of activation of the immune system against primary melanoma. In this study we aimed to investigate the potential roles of HR and TILs on survival, as combined or separately.