Coexistence of regression and tumor infiltrating lymphocytes is associated with more favorable survival in melanoma.

Tas F., Erturk K.

Journal of cancer research and clinical oncology, cilt.147, ss.2721-2729, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 147
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s00432-021-03565-y
  • Dergi Adı: Journal of cancer research and clinical oncology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.2721-2729
  • Anahtar Kelimeler: Melanoma, Regression, Tumor infiltrating lymphocytes, Survival
  • İstanbul Üniversitesi Adresli: Evet

Özet

Purpose Melanoma is one of the highly immunogenic malignancies, and histological regression (HR) and tumor infiltrating lymphocytes (TILs) represent early signs of activation of the immune system against primary melanoma. In this study we aimed to investigate the potential roles of HR and TILs on survival, as combined or separately.