Microbiota stratification identifies disease-specific alterations in neuro-Behcet's disease and multiple sclerosis


Oezguen N., Yalcinkaya N., Kucukali C. I. , Dahdouli M., Hollister E. B. , Luna R. A. , ...Daha Fazla

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.37, ss.58-66, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 37 Konu: 6
  • Basım Tarihi: 2019
  • Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Sayfa Sayıları: ss.58-66

Özet

Objective. Altered gut microbiota community dynamics are implicated in diverse human diseases including inflammatory disorders such as neuro-Behcet's disease (NBD) and multiple sclerosis (MS). Traditionally, microbiota communities are analysed uniformly across control and disease groups, but recent reports of subsample clustering indicate a potential need for analytical stratification. The objectives of this study are to analyse and compare faecal microbiota community signatures of ethno-geographical, age and gender matched adult healthy controls (HC), MS and NBD individuals.