Microbiota stratification identifies disease-specific alterations in neuro-Behcet's disease and multiple sclerosis


Oezguen N., Yalcinkaya N., Kucukali C. I. , Dahdouli M., Hollister E. B. , Luna R. A. , ...More

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.37, no.6, pp.58-66, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 6
  • Publication Date: 2019
  • Title of Journal : CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Page Numbers: pp.58-66

Abstract

Objective. Altered gut microbiota community dynamics are implicated in diverse human diseases including inflammatory disorders such as neuro-Behcet's disease (NBD) and multiple sclerosis (MS). Traditionally, microbiota communities are analysed uniformly across control and disease groups, but recent reports of subsample clustering indicate a potential need for analytical stratification. The objectives of this study are to analyse and compare faecal microbiota community signatures of ethno-geographical, age and gender matched adult healthy controls (HC), MS and NBD individuals.