Dopamine D4 Receptor Gene Exon III VNTR Variant Influences Smoking Status in Turkish Population

Uysal M. A., Sever U., NURSAL A. F., Pehlivan S., Bahadir A., Yurt S., ...More

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, vol.56, no.4, pp.248-252, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.29399/npa.23408
  • Journal Name: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.248-252
  • Keywords: Smoking, Dopamine D4 receptor, gene, variant, POLYMORPHISM, NEUROBIOLOGY
  • Istanbul University Affiliated: Yes

Abstract

Introduction: Dopaminergic gene variants may affect nicotine dependence through their possible impact on the dopamine reward pathway. The purpose of this study is to investigate the relationship between the variable number tandem repeat (VNTR) variant in exon III of the Dopamine D4 receptor (DRD4) gene and genetic predisposition of smoking status in a Turkish population.