Occult HBV infection and YMDD variants in hemodialysis patients with chronic HCV infection


Besisik F. , Karaca Q., Akyuz F., Horosanli S., Onel D., Badur S. , ...Daha Fazla

JOURNAL OF HEPATOLOGY, cilt.38, ss.506-510, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 38 Konu: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0168-8278(02)00457-9
  • Dergi Adı: JOURNAL OF HEPATOLOGY
  • Sayfa Sayıları: ss.506-510

Özet

Background/Aims: End-stage renal disease patients on chronic hemodialysis are at risk for both hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. Although the prevalence is unknown in hemodialysis patients, occult HBV infection is frequent in subjects with chronic HCV infection. We aimed to investigate (1) the prevalence and clinical impact of occult HBV infection in hemodialysis patients with chronic HCV infection, and (2) the frequency of YMDD variants (tyrosine-methionine-aspartate-aspartate amino acid motif of HBV polymerase) in this setting.