Occult HBV infection and YMDD variants in hemodialysis patients with chronic HCV infection


Besisik F., Karaca Q., Akyuz F., Horosanli S., Onel D., Badur S., ...More

JOURNAL OF HEPATOLOGY, vol.38, no.4, pp.506-510, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1016/s0168-8278(02)00457-9
  • Journal Name: JOURNAL OF HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.506-510
  • Istanbul University Affiliated: Yes

Abstract

Background/Aims: End-stage renal disease patients on chronic hemodialysis are at risk for both hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. Although the prevalence is unknown in hemodialysis patients, occult HBV infection is frequent in subjects with chronic HCV infection. We aimed to investigate (1) the prevalence and clinical impact of occult HBV infection in hemodialysis patients with chronic HCV infection, and (2) the frequency of YMDD variants (tyrosine-methionine-aspartate-aspartate amino acid motif of HBV polymerase) in this setting.