Occult HBV infection and YMDD variants in hemodialysis patients with chronic HCV infection

Besisik F., Karaca Q., Akyuz F., Horosanli S., Onel D., Badur S., ...Daha Fazla

JOURNAL OF HEPATOLOGY, cilt.38, sa.4, ss.506-510, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0168-8278(02)00457-9
  • Dergi Adı: JOURNAL OF HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.506-510
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background/Aims: End-stage renal disease patients on chronic hemodialysis are at risk for both hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. Although the prevalence is unknown in hemodialysis patients, occult HBV infection is frequent in subjects with chronic HCV infection. We aimed to investigate (1) the prevalence and clinical impact of occult HBV infection in hemodialysis patients with chronic HCV infection, and (2) the frequency of YMDD variants (tyrosine-methionine-aspartate-aspartate amino acid motif of HBV polymerase) in this setting.