SCOPOLAMINE-INDUCED CONVULSIONS IN FASTED RATS AFTER FOOD INTAKE: THE EFFECT OF DURATION OF FOOD DEPRIVATION


Turkmen A. Z. , NURTEN A., Enginar N.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, cilt.82, ss.47-51, 2019 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 82 Konu: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.26650/iuitfd.411169
  • Dergi Adı: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
  • Sayfa Sayıları: ss.47-51

Özet

Objective: Mice and rats fasted for 2 days and then treated with antimuscarinic drugs, scopolamine or atropine, develop convulsions soon after food intake. It has been demonstrated that deprivation of food for less than 48 h also causes convulsions in mice. Since there are differences in characteristics of the seizures between mice and rats, the present study evaluated whether rats also develop convulsions after being deprived of food for 3-24 h.