In vitro investigation of Sorbus domestica as an enzyme inhibitor

Hasbal G., Yilmaz-Ozden T., Sen M., Yanardag R., Can A.

ISTANBUL JOURNAL OF PHARMACY, vol.50, pp.28-32, 2020 (ESCI) identifier


Background and Aims: Finding new therapeutic enzyme inhibitors by investigating especially medicinal plants is an important research area. The fruits and leaves of Sorbus domestica (service tree) are used as food and folk remedies due to astringent, antidiabetic, diuretic, antiinflammatory, antiatherogenic, antidiarrhoeal, vasoprotective, and vasorelaxant activities, and also used commercially as a vitamin and antioxidant. In this study, the therapeutic effect of S. domestica against diabetes, Alzheimer's disease, aging, and hyperuricemia was investigated.