Development of novel formulations containing Lysozyme and Lactoferrin and evaluation of antibacterial effects on Mutans Streptococci and Lactobacilli


Tonguc-Altin K., Sandalli N., Duman G., Selvi-Kuvuetli S., Topcuoglu N. , Kulekci G.

ARCHIVES OF ORAL BIOLOGY, vol.60, no.5, pp.706-714, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 60 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1016/j.archoralbio.2015.02.004
  • Title of Journal : ARCHIVES OF ORAL BIOLOGY
  • Page Numbers: pp.706-714
  • Keywords: Lysozyme and Lactoferrin, Liposome, Poloxamer 407, Antibacterial effect, PHOSPHOLIPID LIPOSOMES, BIOFILM FORMATION, POLOXAMER 407, IN-VITRO, DELIVERY, SALIVA, LACTOPEROXIDASE, HYDROXYAPATITE, MICROORGANISMS, CHLORHEXIDINE

Abstract

Objective: The aim of this study was to determine the antibacterial effect of different formulations containing Lysozyme and Lactoferrin and drug delivery system as well as poloxamer 407 with the trade name of Pluronic F-127 and/or freeze dried liposome containing DOTAP [freeze dried Liposomal DOTAP] on Streptococcus sobrinus, Streptococcus mutans and Lactobacillus acidophilus in comparison with 0.2% chlorhexidine.