The effect of acute lymphoblastic leukemia treatment on mean cell volume of elytrocytes in children


Celkan T. T., Ozdemir N., Bilgi Z., Oktay G., Apak H., Yildiz I.

TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS, vol.46, no.2, pp.133-136, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.4274/tpa.46.60
  • Journal Name: TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.133-136
  • Keywords: Acute lymphoblastic leukemia, children, mean cell volume (MCV), relapse, MACROCYTOSIS
  • Istanbul University Affiliated: Yes

Abstract

Aim: Mean Cell Volume (MCV) is an easily obtained parameter with the use of automatic blood counters in daily life and is mainly evaluated in the classification of anemias. Treatment protocols that include folic acid antagonists, DNA synthase inhibitors and cyclophosphamide may increase MCV. Our aim was to evaluate MCV changes of children with acute lymphoblastic leukemia under chemotherapy and to compare before and after treatment MCV values in relation to prognosis and relapse.