Corticotropin and cortisol response to maximal exercise testing in central diabetes insipidus


Bas F. , Darendeliler F. F. , Tatli B., Unal M., Kayserilioglu A.

PEDIATRICS INTERNATIONAL, vol.49, no.1, pp.53-57, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.1111/j.1442-200x.2007.02320.x
  • Title of Journal : PEDIATRICS INTERNATIONAL
  • Page Numbers: pp.53-57

Abstract

Background: It is known that arginine vasopressin (AVP) has a stimulatory effect on corticotropin (adrenocorticotropic hormone; ACTH) and cortisol secretion especially during stress. The present study was designed to investigate the effect of stress on ACTH and cortisol levels in patients with central diabetes insipidus (DI) with endogenous AVP deficiency receiving AVP therapy, and to determine whether these children need steroid replacement during stress.