Outcomes of steroid-resistant nephrotic syndrome in children not treated with intensified immunosuppression

Trautmann, Agnes; Seide, Svenja; Lipska-Zietkiewicz, Beata; ÖZALTIN, FATİH; Szczepanska, Maria; Azocar, Marta; Jankauskiene, Augustina; Zurowska, Alexandra; ÇALIŞKAN, SALİM; Saeed, Bassam; Morello, William; Emma, Francesco; Litwin, Mieczyslaw; Tsygin, Alexey; Fomina, Svitlana; Wasilewska, Anna; Melk, Anette; Benetti, Elisa; Gellermann, Jutta; Stajic, Natasa; Tkaczyk, Marcin; Baiko, Sergey; Prikhodina, Larisa; Csaicsich, Dagmar; Medynska, Anna; Krisam, Regina; Breitschwerdt, Heike; Schaefer, Franz

doi:10.1007/s00467-022-05762-4

Outcomes of steroid-resistant nephrotic syndrome in children not treated with intensified immunosuppression

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Trautmann A., Seide S., Lipska-Zietkiewicz B. S., ÖZALTIN F., Szczepanska M., Azocar M., ...More

PEDIATRIC NEPHROLOGY, vol.38, no.5, pp.1499-1511, 2023 (SCI-Expanded)

Publication Type: Article / Article
Volume: 38 Issue: 5
Publication Date: 2023
Doi Number: 10.1007/s00467-022-05762-4
Journal Name: PEDIATRIC NEPHROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
Page Numbers: pp.1499-1511
Keywords: Nephrotic syndrome, Steroid resistance, SRNS, Children, Antiproteinuric treatment, FOCAL SEGMENTAL GLOMERULOSCLEROSIS, CONVERTING ENZYME-INHIBITORS, SPONTANEOUS REMISSION, ANGIOTENSIN BLOCKADE, CYCLOSPORINE-A, TACROLIMUS, ENALAPRIL, THERAPY, TRIAL, PROTEINURIA
Istanbul University Affiliated: No

Abstract

Background The aim of the current PodoNet registry analysis was to evaluate the outcome of steroid-resistant nephrotic syndrome (SRNS) in children who were not treated with intensified immunosuppression (IIS), focusing on the potential for spontaneous remission and the role of angiotensin blockade on proteinuria reduction.