Rosai-Dorfman disease with diffuse gastrointestinal involvement
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.25, sa.7, ss.869-874, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 25 Sayı: 7
- Basım Tarihi: 2013
- Doi Numarası: 10.1097/meg.0b013e32836019f8
- Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.869-874
- İstanbul Üniversitesi Adresli: Evet
Özet
Rosai-Dorfman disease, formerly known as sinus histiocytosis with massive lymphadenopathy', is a rare self-limiting histiocytic proliferative disorder typically presenting early in life with cervical lymphadenopathy and nonspecific systemic symptoms. Although it is usually a nodal disease, extranodal lesions may be encountered in some cases. The gastrointestinal tract is uncommonly affected in Rosai-Dorfman disease and its diagnosis depends on clinical suspicion and careful histopathological examination of biopsy samples taken from involved gastrointestinal segments. Here, we report a case of atypical Rosai-Dorfman disease with systemic symptoms and diffuse gastrointestinal involvement that led to a diagnostic and therapeutic challenge. (C) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.