Journal of Clinical Medicine of Kazakhstan, vol.2, no.56, pp.11-16, 2020 (Peer-Reviewed Journal)
Aim: The aim of the present study was to investigate whether salivary
alpha-amylase levels could be decreased by conscious sedation in the patients
undergoing impacted third molar extraction.
Material and methods: A total of 18 male patients were recruited. All
patients were administered the Modified Dental Anxiety Scale test. Patients
were divided into a test group (procedures under sedation) and a control group
(procedures under local anesthesia). Systolic blood pressure, diastolic blood
pressure, oxygen saturation, and heart rate were monitored at different study
time-points. Five samples of saliva were taken from each patient: the first time
the patient came to the clinic, the patient sat in the chair for extraction, before
local anesthesia, immediately after extraction, at 4 h after extraction.
Results: Although no statistically important difference was found for
systolic blood pressure (p>0.05) between groups, postoperative diastolic blood
pressure level of control group was statistically higher than the test group
(p=0.030). Also, a statistically significant decrease was found in the oxygen
saturation level in postoperative time compared to preoperative time (p<0.05).
Conclusion: Even though conscious sedation may be a solution for dental
anxiety and phobia, our results indicated that sedation did not affect acute stress
levels during oral surgery.
Key words: conscious sedation, dental anxiety, stress biomarkers, salivary
alpha-amylase, tooth extraction