Dose-dependent neuroprotective effects of melatonin on experimental spinal cord injury in rats


Gul S., Celik S., Kalayci M., Tasyurekli M., Cokar N., Bilge T.

SURGICAL NEUROLOGY, vol.64, no.4, pp.355-361, 2005 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 64 Issue: 4
  • Publication Date: 2005
  • Doi Number: 10.1016/j.surneu.2005.03.036
  • Journal Name: SURGICAL NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.355-361
  • Istanbul University Affiliated: No

Abstract

Background: This report examines the dose-dependent effects of melatonin on early lipid peroxidation levels, ultrastructural changes, and neurological function in experimental spinal cord injury (SCI) by comparing them with therapeutic levels of methylprednisolone in rats.