Bispectral Index Dynamics During Propofol Hypnosis Is Similar in Red-Haired and Dark-Haired Subjects

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Doufas A. G., Orhan-Sungur M., Komatsu R., Lauber R., Akca O., Shafer S. L., ...More

ANESTHESIA AND ANALGESIA, vol.116, pp.319-326, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 116
  • Publication Date: 2013
  • Doi Number: 10.1213/ane.0b013e31827533b4
  • Journal Name: ANESTHESIA AND ANALGESIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.319-326
  • Istanbul University Affiliated: No

Abstract

BACKGROUND: We have previously shown that red hair is associated with increased desflurane requirement for immobility, compared with dark hair. The effect of red hair on IV anesthetic requirement remains unknown. We tested the hypothesis that the propofol concentration in the effect site associated with half maximal electroencephalogram response, Ce-50 is at least 50% higher in subjects with red hair.