Immunohistochemical Localization of Glutathione S-Transferase Isoenzymes (GSTA, GSTP, GSTM4, and GSTT1) and Tumour Marker p53 in Matched Tissue from Normal Larynx and Laryngeal Carcinoma: Correlations with Prognostic Factors

Sedat, Sedat; Serpil, Oguztuzun; Nurdan, Gurbuz; Aylin, Gul; Arif, Sanli; Muzeyyen, Ozhavzali; Bulent, Satar; Sezen, Ozan; Nimet, Karadayi

doi:10.2310/7070.2010.090142

Immunohistochemical Localization of Glutathione S-Transferase Isoenzymes (GSTA, GSTP, GSTM4, and GSTT1) and Tumour Marker p53 in Matched Tissue from Normal Larynx and Laryngeal Carcinoma: Correlations with Prognostic Factors

Atıf İçin Kopyala

Sedat A., Serpil O., Nurdan G., Aylin G., Arif S., Muzeyyen O., ...Daha Fazla

JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, cilt.39, sa.5, ss.542-550, 2010 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39 Sayı: 5
Basım Tarihi: 2010
Doi Numarası: 10.2310/7070.2010.090142
Dergi Adı: JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.542-550
İstanbul Üniversitesi Adresli: Hayır

Özet

Objective: The immunohistochemical staining characteristics of glutathione S-transferase (GST) alpha (GSTA), pi (GSTP), mu (GSTM4), and theta (GSTT1) and P53 were investigated in laryngeal squamous cell carcinoma (LSCC) cases and normal laryngeal tissue from 46 patients. The relationships between expression of the GST isoenzymes and some clinicopathologic features were also examined.