Immunohistochemical Localization of Glutathione S-Transferase Isoenzymes (GSTA, GSTP, GSTM4, and GSTT1) and Tumour Marker p53 in Matched Tissue from Normal Larynx and Laryngeal Carcinoma: Correlations with Prognostic Factors


Sedat A. , Serpil O., Nurdan G., Aylin G., Arif S., Muzeyyen O., ...Daha Fazla

JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, cilt.39, ss.542-550, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 39 Konu: 5
  • Basım Tarihi: 2010
  • Doi Numarası: 10.2310/7070.2010.090142
  • Dergi Adı: JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
  • Sayfa Sayıları: ss.542-550

Özet

Objective: The immunohistochemical staining characteristics of glutathione S-transferase (GST) alpha (GSTA), pi (GSTP), mu (GSTM4), and theta (GSTT1) and P53 were investigated in laryngeal squamous cell carcinoma (LSCC) cases and normal laryngeal tissue from 46 patients. The relationships between expression of the GST isoenzymes and some clinicopathologic features were also examined.