The comparison of SUVmax values in 18F-FDG PET/CT according to cell type, stage, lymph node involvement and metastasis in lung cancers


Çalışkan T., Canoğlu K., Işık E. G.

Gulhane Medical Journal, cilt.63, sa.4, ss.292-296, 2021 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.4274/gulhane.galenos.2021.1658
  • Dergi Adı: Gulhane Medical Journal
  • Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.292-296
  • Anahtar Kelimeler: 18F FDG PET/CT, positron-emission tomography, metastasis, tumor staging, Lung cancer
  • İstanbul Üniversitesi Adresli: Evet

Özet

© 2021. by the University of Health Sciences Turkey, Gülhane Faculty of Medicine / Gülhane Medical Journal published by Galenos Publishing House. All Rights Reserved.Aims: 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computerized tomography (PET/CT) provides metabolic information in addition to anatomic extension. This study aimed to compare the primary tumor maximum standardized uptake values (SUVmax) on PET/CT according to the histopathological type, stage, nodal involvement, and the metastasis of lung cancers. Methods: In this retrospective study, PET/CTs of the patients with lung cancer were examined. Staging of the cancer was performed according to the eighth (8th) edition of the tumor, node and metastasis (TNM) classification system. SUVmax values were recorded and compared. Results: Two hundred thirty-three patients with lung cancer (78.5% male, mean age: 67.0±9.6 years, range: 47-91 years) were analyzed. The SUVmax value of squamous cell carcinoma (SCC) (15.2±7.6) was higher than the SUVmax values of adenocarcinoma (AC) and small cell lung carcinoma (SCLC) (10.9±5.6 and 12.2±5.5, respectively, p<0.001). SUVmax values were not different between the stages of AC, SCC and SCLC (p=0.285, p=0.377 and p=0.061, respectively). SUVmax values were similar between nodal involvements (p=0.490, p=0.645 and p=0.114 for AC, SCC, and SCLC, respectively). There was no difference in SUVmax values of lung cancers with and without metastasis (p=0.496, p=0.209, and p=0.544 for AC, SCC, and SCLC, respectively). Conclusions: The SUVmax value of SCC was highest among lung cancers. There was no significant difference between the SUVmax value of the primary tumor on PET/CT and the TNM stages of the tumor.