SET oncogene is upregulated in pediatric acute lymphoblastic leukemia.

Ekmekci, SEMA; Ekmekci, Cumhur; Kandilci, Ayten; Gulec, ÇAĞRI; Akbiyik, Meral; Emrence, ZELİHA; Abaci, NESLİHAN; Karakas, ZEYNEP; Agaoglu, Leyla; Unuvar, AYŞEGÜL; Anak, Sema; Devecioglu, Omer; Ustek, Duran; Grosveld, Gerard; Ozbek, Ugur

doi:10.1700/1088.11938

SET oncogene is upregulated in pediatric acute lymphoblastic leukemia.

Ekmekci S. S., Ekmekci C. G., Kandilci A., Gulec Ç., Akbiyik M., Emrence Z., ...Daha Fazla

Tumori, cilt.98, sa.2, ss.252-6, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 98 Sayı: 2
Basım Tarihi: 2012
Doi Numarası: 10.1700/1088.11938
Dergi Adı: Tumori
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.252-6
İstanbul Üniversitesi Adresli: Evet

Özet

Aims and background. The SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It has been shown that SET is upregulated in BCR-ABL1-positive cell lines, patient-derived chronic myeloid leukemia CD34-positive cells, and some solid tumors.