SET oncogene is upregulated in pediatric acute lymphoblastic leukemia.


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Ekmekci S. S., Ekmekci C. G., Kandilci A., Gulec Ç., Akbiyik M., Emrence Z., ...Daha Fazla

Tumori, cilt.98, sa.2, ss.252-6, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 98 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1700/1088.11938
  • Dergi Adı: Tumori
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.252-6
  • İstanbul Üniversitesi Adresli: Evet

Özet

Aims and background. The SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It has been shown that SET is upregulated in BCR-ABL1-positive cell lines, patient-derived chronic myeloid leukemia CD34-positive cells, and some solid tumors.