SET oncogene is upregulated in pediatric acute lymphoblastic leukemia.


Creative Commons License

Ekmekci S. S. , Ekmekci C. G. , Kandilci A., Gulec Ç. , Akbiyik M., Emrence Z. , ...Daha Fazla

Tumori, cilt.98, ss.252-6, 2012 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 98 Konu: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1700/1088.11938
  • Dergi Adı: Tumori
  • Sayfa Sayıları: ss.252-6

Özet

Aims and background. The SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It has been shown that SET is upregulated in BCR-ABL1-positive cell lines, patient-derived chronic myeloid leukemia CD34-positive cells, and some solid tumors.