SET oncogene is upregulated in pediatric acute lymphoblastic leukemia.

Creative Commons License

Ekmekci S. S., Ekmekci C. G., Kandilci A., Gulec Ç., Akbiyik M., Emrence Z., ...More

Tumori, vol.98, no.2, pp.252-6, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 98 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1700/1088.11938
  • Journal Name: Tumori
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.252-6
  • Istanbul University Affiliated: Yes

Abstract

Aims and background. The SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It has been shown that SET is upregulated in BCR-ABL1-positive cell lines, patient-derived chronic myeloid leukemia CD34-positive cells, and some solid tumors.