Possible relationship between the resistin gene C-420G polymorphism and colorectal cancer in a Turkish population

Creative Commons License

Düzköylü Y., Arıkan S., Turan S., Yaylim I., Doğan M. B., Sarı S., ...More

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.26, no.5, pp.392-396, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.5152/tjg.2015.0188
  • Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.392-396
  • Keywords: Colorectal cancer, gene polymorphism, resistin, INSULIN-RESISTANCE, ADIPOSE-TISSUE, PROMOTER, GENOTYPE, RISK, INFLAMMATION, ASSOCIATION, ADIPONECTIN, EXPRESSION
  • Istanbul University Affiliated: Yes

Abstract

Background/Aims: In recent years, with improvements in genotyping, a possible relationship between obesity-related gene polymorphisms and colorectal cancer (CRC) has been studied. The promoter region C-420G of the resistin gene is believed to have an important role in the development of malignancy. We prospectively evaluated the possible effect of the resistin C-420G polymorphism on the risk and prognosis of CRC.