PTPN22 gene polymorphism in Takayasu's arteritis.

Sahin N., AKSU K., Kamali S., Bicakcigil M., OEZBALKAN Z., Fresko I., ...Daha Fazla

Rheumatology (Oxford, England), cilt.47, sa.5, ss.634-5, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 5
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1093/rheumatology/ken106
  • Dergi Adı: Rheumatology (Oxford, England)
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.634-5
  • Anahtar Kelimeler: Takayasu's arteritis, single nucleotide polymorphism, PTPN22, SINGLE-NUCLEOTIDE POLYMORPHISM, LYMPHOID TYROSINE PHOSPHATASE, ASSOCIATION, CLASSIFICATION, ALLELE
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective. Takayasus arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase.