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Sahin N., AKSU K., Kamali S., Bicakcigil M., OEZBALKAN Z., Fresko I., ...More
Rheumatology (Oxford, England), vol.47, no.5, pp.634-5, 2008 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
47
Issue:
5
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Publication Date:
2008
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Doi Number:
10.1093/rheumatology/ken106
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Journal Name:
Rheumatology (Oxford, England)
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.634-5
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Keywords:
Takayasu's arteritis, single nucleotide polymorphism, PTPN22, SINGLE-NUCLEOTIDE POLYMORPHISM, LYMPHOID TYROSINE PHOSPHATASE, ASSOCIATION, CLASSIFICATION, ALLELE
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Istanbul University Affiliated:
Yes
Abstract
Objective. Takayasus arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase.