Effects of intravenous immunoglobulin therapy on behavior deficits and functions in sepsis model

Ozcan, Perihan; Senturk, Evren; Orhun, GÜNSELİ; Gumru, Salih; Arican, NADİR; Orhan, NURCAN; Yilmaz, Canan; Kaya, Mehmet; ARICIOĞLU, FEYZA; Esen, FİGEN

doi:10.1186/s13613-015-0062-z

Effects of intravenous immunoglobulin therapy on behavior deficits and functions in sepsis model

Ozcan P. E., Senturk E., Orhun G., Gumru S., Arican N., Orhan N., ...Daha Fazla

ANNALS OF INTENSIVE CARE, cilt.5, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 5
Basım Tarihi: 2015
Doi Numarası: 10.1186/s13613-015-0062-z
Dergi Adı: ANNALS OF INTENSIVE CARE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: Sepsis, Immunoglobulins, Cecal ligation and puncture, Plus maze test, Forced swimming test, Behavioral alteration, BLOOD-BRAIN-BARRIER, CECAL LIGATION, COGNITIVE IMPAIRMENT, RATS, MEMORY, INHIBITION, PARAMETERS, BREAKDOWN, REVERSES, STRESS
İstanbul Üniversitesi Adresli: Evet

Özet

Background: We aim to demonstrate behavioral alterations in a sepsis model using intravenous (IV) immunoglobulin G (IgG) and immunoglobulins enriched with IgA and IgM (IgGAM).