Increased DNA-Glycation in Type 2 Diabetic Patients: The Effect of Thiamine and Pyridoxine Therapy

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Polizzi F. C., Andican G., Cetin E., Civelek S., Yumuk V. D., Burcak G.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, vol.120, no.6, pp.329-334, 2012 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 120 Issue: 6
• Publication Date: 2012
• Doi Number: 10.1055/s-0031-1298016
• Journal Name: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.329-334
• Istanbul University Affiliated: Yes

Abstract

Background: It is well known that advanced glycation plays an important role in the progression of diabetic complications. Although several studies have been done on protein glycation, studies related to DNA glycation is limited. The aim of this study is primarily to investigate DNA glycation in diabetes mellitus and secondarily to observe the effects of vitamins B-1 and B-6.