Comparison of the distinctive pathological features of and p16 and c-Kit expression levels in benign and malignant endometrial polyps


Koc N., Ayas S., UYGUR L., Ozel Ozbay N.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.46, no.6, pp.1822-1828, 2016 (SCI-Expanded, Scopus, TRDizin)

  • Publication Type: Article / Article
  • Volume: 46 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.3906/sag-1508-39
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1822-1828
  • Keywords: p16, c-Kit, endometrial polyp, tubal metaplasia, CD117, ADENOCARCINOMA, TRANSFORMATION, HYPERPLASIA, METAPLASIA, P16(INK4A), CARCINOMA, DIAGNOSIS, TISSUES, CANCER
  • Istanbul University Affiliated: No

Abstract

Background/aim: Histopathological examination is crucial for the effective management of endometrial polyps. Immunohistochemical markers such as p16 and c-Kit may facilitate the differential diagnoses of benign and malignant polyps. The aim of the present study was to explore the expression levels of c-Kit (CD117) and p16 in endometrial polyps of postmenopausal women.