The effect of heme oxygenase-1 induction by glutamine on TNBS-induced colitis - The effect of glutamine on TNBS colitis

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Giris M., Erbil Y., Dogru-Abbasoglu S., YANIK B. T., AHS H., Olgaç V., ...More

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, vol.22, no.6, pp.591-599, 2007 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 22 Issue: 6
• Publication Date: 2007
• Doi Number: 10.1007/s00384-006-0238-y
• Journal Name: INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.591-599
• Istanbul University Affiliated: Yes

Abstract

Background Inflammatory bowel disease is a multifactorial inflammatory disease of the colon and rectum with an unknown etiology. In the present study, we aimed to investigate whether heme oxygenase-1 (HO-1) induction by glutamine could protect colitis-induced damage from oxidative, inflammatory, and apoptotic damage.