International Journal of Radiation Research, cilt.15, sa.4, ss.353-362, 2017 (SCI-Expanded)
Background: The aim of this study was to compare the differences of the dosimetric parameters between three-dimensional conformal radiotherapy (3D-CRT) and simultaneous-integrated boost intensity-modulated radiotherapy (SIB-IMRT) techniques in the prone and supine posi ons for breast irradia on. Materials and Methods: Ten pa ents underwent a computed tomography simula on in both the prone and supine posi ons. For each set-up posi on, the treatment plans were created with 3D-CRT and SIBIMRT. The dosimetric parameters were obtained from dose-volume histograms. Results: High-dose regions in the whole breast were decreased in IMRT with a simultaneous integrated boost technique. The lung doses were significantly reduced for all pa ents, and the heart doses were lower in lesided breast cancer pa ents in the prone posi on. The heart doses except mean dose were not significantly lower with SIB-IMRT in the prone posi on. Conclusion: SIB-IMRT allowed a more conformal dose distribu on regardless of posi on. The prone posi on is superior to the supine treatment regarding doses in the ipsilateral, contralateral lung, and heart. The contralateral breast doses were increased in the prone posi on. Prone IMRT can be chosen for simultaneous integrated boost treatment in women with pendulous breasts.