Modulation of innate and adaptive immune responses by arabinoxylans

Fadel A., Plunkett A., Li W., Gyamfi V. E. T., Nyaranga R. R., Fadel F., ...Daha Fazla

JOURNAL OF FOOD BIOCHEMISTRY, cilt.42, sa.2, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 42 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1111/jfbc.12473
  • Dergi Adı: JOURNAL OF FOOD BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • İstanbul Üniversitesi Adresli: Evet

Özet

Humans are exposed to harmful pathogens and a wide range of noxious substances every day. The immune system reacts to, and destroys, these pathogens and harmful substances. The immune system is composed of innate and adaptive immunity, which liaise to protect the host and maintain health. Foods, especially cereals, have been reported to modulate the immune response. Arabinoxylans are nonstarch polysaccharides that have been shown to possess immune-modulatory activities. This review article discusses the fundamentals of the immune system and provides an overview of the immunomodulatory potential of arabinoxylans in conjunction with their structural characteristics and proposed similarities with lipopolysaccharides.