INTER-POPULATION COMPARISONS AND THE IMPORTANCE IN INFECTIOUS DISEASES OF THE IRF7, TBK1, IFNAR1, IFNAR2 AND TLR3 GENE VARIANTS IN TURKISH INDIVIDUALS

Karacan, Asli; Toksoy, Güven; Uyguner, Zehra; Karaman, Birsen; Basaran, Seher; Komurcu-Bayrak, Ayşe

doi:10.26650/iuitfd.1060030

INTER-POPULATION COMPARISONS AND THE IMPORTANCE IN INFECTIOUS DISEASES OF THE IRF7, TBK1, IFNAR1, IFNAR2 AND TLR3 GENE VARIANTS IN TURKISH INDIVIDUALS

Atıf İçin Kopyala

Karacan A., Toksoy G., Uyguner O., Karaman B., Basaran S., Komurcu-Bayrak E.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, cilt.85, sa.3, ss.344-354, 2022 (Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 85 Sayı: 3
Basım Tarihi: 2022
Doi Numarası: 10.26650/iuitfd.1060030
Dergi Adı: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
Derginin Tarandığı İndeksler: Scopus
Sayfa Sayıları: ss.344-354
Anahtar Kelimeler: Infectious diseases, population, immunity genes, variant, MEDICAL GENETICS, AMERICAN-COLLEGE, GENOMICS
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: In the research conducted during the pandemic period, it has been determined that IRF7, TBK1, IFNAR1, IFNAR2, and TLR3 immunity genes play an important role in the predisposition to SARS-CoV-2 infection. However, there is no information about variants of these genes in the Turkish population. The aim of this study was to determine the variants specific to the our study's population in these genes that predispose to infections and to compare them with other populations.