Constant-rate infusion is a drug administration method which drug is given intravenously at the desired drug amount per minute in solutions. In veterinary clinics, electronic infusion pumps and monitorization devices are becoming widespread because of technological advance. This has created the possibility of using many drugs in veterinary medicine that are used in the human emergency medicine and intensive care with constant-rate infusion.
In constant-rate infusion method; cardiovascular, analgesic, anesthetic, diuretic and antimicrobial drugs are administered continuously in an intravenous solution with the constant flow so that plasma concentrations remain steady. This method removes the difference between the maximum and minimum plasma concentrations of drugs administered at regular intervals and in this wise, helps to decrease the plasma concentration fluctuation in drugs which have short half-lives and reduce the potential of adverse effects in low safety index drugs. Despite the advantages, the lack of knowledge and experience in the subject and the mathematical difficulties of dose calculation on time basis, prevent the use of drugs with constant rate infusion widely.
For this purpose, we think that gaining information about the use of drugs that can be used with this method, creating simple methods for dosage calculation will help to spread the use of drugs with constant-rate infusion.Constant-rate infusion is a drug administration method which drug is given intravenously at the desired drug amount per minute in solutions. In veterinary clinics, electronic infusion pumps and monitorization devices are becoming widespread because of technological advance. This has created the possibility of using many drugs in veterinary medicine that are used in the human emergency medicine and intensive care with constant-rate infusion.
In constant-rate infusion method; cardiovascular, analgesic, anesthetic, diuretic and antimicrobial drugs are administered continuously in an intravenous solution with the constant flow so that plasma concentrations remain steady. This method removes the difference between the maximum and minimum plasma concentrations of drugs administered at regular intervals and in this wise, helps to decrease the plasma concentration fluctuation in drugs which have short half-lives and reduce the potential of adverse effects in low safety index drugs. Despite the advantages, the lack of knowledge and experience in the subject and the mathematical difficulties of dose calculation on time basis, prevent the use of drugs with constant rate infusion widely.
For this purpose, we think that gaining information about the use of drugs that can be used with this method, creating simple methods for dosage calculation will help to spread the use of drugs with constant-rate infusion.