The role of anticonvulsants in treatment-resistant anxiety disorders
KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, vol.19, 2009 (SCI-Expanded, TRDizin)
- Publication Type: Article / Article
- Volume: 19
- Publication Date: 2009
- Journal Name: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
- Istanbul University Affiliated: Yes
Abstract
Antidepressants are the first-line pharmacological treatment approach for the anxiety disorders. Other pharmacotherapy options for anxiety disorders include benzodiazepines, atypical antipsychotics, and anticonvulsants. Evidence provided by double-blind, placebo-controlled trials demonstrates the effectiveness of pregabalin and valproic acid for generalized anxiety disorder, pregabalin and gabapentin for social anxiety disorder, valproic acid for panic disorder, and lamotrigine for posttraumatic stress disorder. Further research is needed to determine the efficacy of anticonvulsants for the treatment-resistant anxiety disorder patients.